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Conception : la start-up qui vise la fabrication de gamètes humaines.

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Conception : cette start-up californienne cherche à mettre au point un procédé de fabrication de gamètes humaines. C’est ce que rapporte un article récent du MIT Review : “Today the company (…) called Conception, is the largest commercial venture pursuing what’s called in vitro gametogenesis, which refers to turning adult cells into gametes—sperm or egg cells. It employs around 16 scientists and has raised $20 million from well-known tech figures including Sam Altman, the CEO of OpenAI and former president of Y Combinator; Jaan Tallinn, one of the founders of Skype; and Blake Borgeson, a cofounder of Recursion Pharmaceuticals » relate Antonio Regalado. 

Si l’opération a été menée en 2016 sur des souris, l’objectif reste pour l‘instant hors de portée «Conception is starting with blood cells from female donors and trying to transform these into the first “proof-of-concept human egg” made in the lab. The company hasn’t done it yet—nor has anyone else. There are still scientific puzzles to overcome, but (…)  artificial eggs “could become one of the most important technologies ever created. That’s no exaggeration. If scientists can generate supplies of eggs, it would break the rules of reproduction as we know them. Women without ovaries—for example, because of cancer or surgery—might be able to have biologically related children. What’s more, lab-made eggs would cancel the age limits on female fertility, allowing women to have related babies at 50, 60, or even beyond. La création de gamètes à partir d’une cellule de sang ouvrirait la porte à une reproduction issue d’une seule personne. Elle pourrait également permettre, puisqu’une grande quantité de gamètes serait disponible, de sélectionner in vitro des embryons avant leur réimplantation. Les informations relatées par le MIT Review ne sont pas à prendre à la légère : les implications de la mise en fabrication de gamètes humaines, de gamètes humaines envisagées comme des produits industriels, seraient abyssales.

 

https://www.technologyreview.com/2021/10/28/1038172/conception-eggs-reproduction-vitro-gametogenesis/

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