Des avancées dans le domaine de la fabrication de spermatozoïdes et ovocytes humaines en laboratoire sont en cours. La méthode utilisée n’est plus celle de la reprogrammation de cellules somatiques en cellules souches, mais une méthode qui s’apparente à celle du “clonage” utilisée pour donner naissance à la brebis Dolly en Grande Bretagne en 1996. Dans cette expérience menée par Shoukhrat Mitalipov,  Oregon Health & Science University et publiée dans Nature Communications, les oeufs humains obtenus à partir de cellules de peau ont été fertilisés : “Another approach has appeared on the scene. Based on somatic-cell nuclear transfer, the cloning technique that made Dolly the sheep in the 1990s, American scientists have managed to get the DNA from a woman’s skin cell into a donated egg cell (from which they had removed the nucleus). They also worked out a way to roughly halve the “new” egg’s number of chromosomes, so that there is room for a sperm to fertilise the egg and contribute its genes. In this way they made a handful of early embryos. But the technique is still far from the clinic. All these embryos had chromosomal abnormalities because the researchers have yet to work out how to control exactly which chromosomes (and how many of them) are kept in the egg and which are removed from it. No babies will be born this way until they sort out that crucial step. Nevertheless the race to revolutionise human reproduction once again is on” rapporte the Economist https://www.economist.com/science-and-technology/2025/09/30/a-new-technique-can-